ESC European Society of Cardiology,update

 

My ESC News 20 May 2026 - A Weekly Update of ESC Events & Resources

Avoidable inequalities remain in cardiovascular disease burden and care   The latest cardiovascular disease statistics from the ESC Atlas of Cardiology, just published in the European Heart Journal, show that cardiovascular disease remains the leading health challenge in ESC member countries, causing over 3 million deaths and 68 million healthy life years lost each year. Progress in cardiovascular medicine is at risk of being offset by the high prevalence of risk factors such as hypertension, dyslipidaemia and obesity. Middle-income countries continue to face nearly double the CVD mortality of high-income nations, highlighting the urgent need for stronger health system investment and more equitable care.   Read the paper   Access and compare your country’s data on the Atlas of Cardiovascular statistics website.

Cardiovascular Science ESC journals - recent articles   Enjoy free access today to: European Heart Journal: A nurse-coordinated intervention programme vs standard of care after an acute coronary syndrome: the ALLEPRE trial. Discover European Heart Journal: Cancer and heart failure: prevalence, incidence, and prognosis in Scotland. Discover European Heart Journal - Cardiovascular Pharmacotherapy: Effectiveness and safety of SGLT2 inhibitor initiation in sacubitril-valsartan users with heart failure: a population-based cohort study. Discover European Heart Journal - Cardiovascular Imaging: Carotid plaque inflammation and calcification on somatostatin receptor PET/CT imaging predict stroke and major adverse cardiovascular events. Discover European Journal of Cardiovascular Nursing: Bridging insigHts from the MEdical Information Department with alirocumab pen use for a better pAtient jouRney and HCP-Community engagement (HEAR Project). Discover European Heart Journal - Digital Health: Novel machine learning fusion architectures integrating electrocardiogram representations: applications to acute coronary event detection. Discover EP Europace: Safety and effectiveness of the TactiFlex Duo System: 6-month results of the FOCALFLEX Study. Discover European Journal of Preventive Cardiology: ASCVD risk stratification using apolipoprotein B and the LDL-C to total cholesterol ratio. Discover Translational Science for You   Metabolomic fingerprints reveal distinct mechanisms in HFpEF and HFrEF Heart failure is accompanied by profound metabolic remodelling, but distinct biochemical signatures in HFpEF and HFrEF remain poorly characterised. In this study, large-scale metabolomic profiling identified phenotype-specific metabolic networks associated with morbidity and mortality. Nitric oxide signalling and purine metabolism emerged as key prognostic pathways in HFpEF, whereas acylcarnitine and amino acid metabolism were strongly linked to outcomes in HFrEF. Discover more about metabolism-driven mechanisms and prognostic insights in the full study.   ALCAT1 inhibition restores mitochondrial integrity and reverses cardiac remodelling Mitochondrial remodelling is a central feature of heart failure pathophysiology, yet effective targeted therapies remain limited. Pressure overload-induced cardiac stress drives profound metabolic and structural changes, contributing to hypertrophy, dysfunction, inflammation, and fibrosis. ALCAT1-mediated pathological cardiolipin remodelling was shown to accelerate these processes through mitochondrial injury and depletion of tetralinoleoyl cardiolipin. Genetic deletion or pharmacological inhibition of ALCAT1 with dafaglitapin restored mitochondrial function and reduced adverse cardiac remodelling in vivo. The full study provides further insight into mitochondrial lipid remodelling and emerging therapeutic opportunities in pressure overload-induced heart failure.   Free session on ESC 365   If you couldn't attend ESC Preventive Cardiology 2026 in Ljubljana, you can still watch the session 'Guidelines in practice: hypertension on both sides of the Atlantic'. It is now free to access on ESC 365 for a limited time. Just sign into your My ESC account to start watching. "Three guidelines, three typical cases, multiple interpretations – yet a single message emerges: look beyond the office BP reading and treat the person, not just the numbers." Nicolle Kraenkel, Congress Programme Committee Chair.    ESC Chat achieves CE Class I certification   This certification under the EU Medical Device Regulation recognises ESC Chat as a trusted resource for healthcare professionals, providing easy access to ESC Guidelines. Its responses are grounded in ESC guidance, with clear structure and referenced sources. Discover how ESC Chat can support your clinical practice.   News from Our Communities In Memoriam   The ESC pays tribute to Prof. Ronen Beeri A highly respected cardiologist and a committed contributor to ESC educational activities, Prof. Beeri played a key role in advancing education within the ESC.   "Through his expertise, engagement, and thoughtful guidance, Prof. Beeri made a lasting contribution to ESC education and to the wider cardiovascular community. His input was always marked by rigour, collegiality, and a strong commitment to excellence in training and professional development," said Prof. Thomas Luescher, ESC President. The ESC extends its sincere condolences to his family, colleagues, and all those who had the privilege of working with him. His contribution to cardiovascular education and to the ESC will be gratefully remembered.   World Hypertension Day – 17 May   This year's theme was 'Controlling Hypertension Together!'. The ESC Council on Hypertension has gathered a wide selection of resources for you designed to inform, inspire, and support your daily practice. Discover the resources.   Hot off the press   Heart Failure 2026 If you missed the coverage from our leading heart failure congress, catch up on key messages and visual summaries across our social media channels #HeartFailure26. Here's what was hot in the media! Findings from the first randomised trial assessing RNA therapy in heart failure. Read the release. New positive data on old drugs: Digitalis reduces heart failure events. Read the release. ‘Lemon-on-sticks’ phenotype indicates poor prognosis in heart failure. Read the release.    Post of the Week   Education and Career Development CardioPractice – Women and the Heart   In May, CardioPractice continues its two-part series on 'Women and the Heart', with an article exploring how cardiovascular risk evolves across each stage of a woman’s life and how a more integrated, holistic approach can support better outcomes. Discover the resources.   AcuteCVDays – Update on the spectrum of cardiogenic shock   Throughout May, boost your knowledge with free access to educational resources on the spectrum of cardiogenic shock.   Explore clinical cases, expert opinions and best practices, and test your knowledge with quizzes.   This week's topic, in collaboration with the EACVI: When the right heart fails: managing acute right ventricular shock.   ESC TV Today – updates and insights from the experts   Theresa McDonagh highlights key findings from Heart Failure 2026, including new data on digitalis use, subcutaneous furosemide, and oxygen saturation targets in decompensated heart failure.   As biomarkers gain importance in heart failure care, Lynne Warner Stevenson explores how NT-proBNP and emerging tools can enhance diagnosis, guide treatment, and enable personalised risk assessment. With new evidence from the DECISION trial and recent analyses, Dirk van Veldhuisen reassesses the role of digoxin in modern heart failure treatment and its potential benefits. Watch the full episode.   Image of the Week     This week's image was submitted by Liabot Quentin and David Meier from CHUV Lausanne, Switzerland. What does this OCT image show?   Answer now   Do you have an interesting case to share? Submit it today   Upcoming webinars   TODAY, 20 May: Prevention in women: CAD, atrial fibrillation, heart failure and risk factors across the lifespan. Register Monday, 25 May: Smart choices in lead management: balancing risks, selecting patients, and ensuring cost-effectiveness. Register   Congresses ESC Congress 2026 28–31 August Munich & Online   Transform your career at #ESCCongress    "The fully integrated Young Track allows real opportunities for interaction, mentorship, and career development." Christian Camm, Chair of the ESC Young Committee. Explore The Young Community Track for practical career guidance, direct access to experts, and connections that can shape what comes next. Register before 31 May to save the most!   ESC Digital & AI Summit 12–13 November Basel, Switzerland   The deadline for #ESCAIsummit26 submissions is in one week. Built for professionals shaping what comes next in digital cardiology, this is where clinicians, researchers, engineers and innovators unite to test ideas and move practical solutions forward. Submit your abstract, technology or innovation by 28 May to gain expert feedback and open the door to meaningful collaboration. Bring a real-world challenge as a Hackathon topic and see how it stands up in a live setting.   Upcoming deadline   EACVI 2026: Abstract submission deadline - TOMORROW, 21 May.

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